Development of chronic renal failure can be divided into several stages ?

Patients Question: development of chronic renal failure can be divided into several stages ?
Experts Re: chronic renal failure ( chronic renal failure ) , occurs on the basis of a variety of chronic kidney disease on . After several months or years , renal dysfunction , resulting in metabolic wastes ( uremic toxins ) in the body and moisture accumulation in the body, a series of clinical symptoms of kidney function at this time is called " failure ." Many patients at the beginning of decline of renal function failed to detect until kidney damage has been discovered more than 70 percent . Chronic renal failure clinically divided into four stages , namely, decreased renal reserve force of ( compensatory phase ) , azotemia , renal failure and uremia .
A kidney Reserve in life:
Assuming normal renal function, renal entire reserve capacity ( usually made ​​on clinical indicators by creatinine clearance ) , then at this time , despite the reduction in glomerular filtration rate , but still more than 30 % to 70 %, the although the decline in renal reserve force , but the renal excretory function able to maintain a stable internal environment , the patient may have no clinical feel and without azotemia . This period is often a normal serum creatinine .
Second, renal insufficiency period :
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That is often said azotemia , chronic renal failure is a prelude , then reduce to a normal glomerular filtration rate of 20% to 30 % the ability to maintain a stable internal environment has been some damage , may have a slight azotemia, renal concentration damage usually presents with mild polyuria and nocturia , and may have mild anemia . Under normal circumstances this stage , often without obvious symptoms , but if there is an additional burden on the body , such as hypovolemia, infections, urinary tract obstruction or use of nephrotoxic drugs, patients may even renal failure uremia symptoms quickly such as correcting an additional burden , the symptoms can be reversed. Restored to the original stable state. This term is often elevated in serum creatinine .
Third, renal failure :
When the reduction in glomerular filtration rate to the normal 11% to 20 %, the internal environment has long-term , sustained abnormal , there was a significant azotemia , anemia than obvious , concentrated functional disorders often show significant to isotonic urine, nocturia , and water and electrolyte imbalance, such as light or moderate metabolic acidosis , sodium retention , hypocalcemia , hyperphosphatemia and so on. Generally no hyperkalemia , may have mild gastrointestinal , cardiovascular and central nervous system symptoms. This period is often between serum creatinine 451 ~ 707μmo1 / L.

Fourth, advanced renal failure ( uremia ) :